pharmjournalРазработка и регистрация лекарственных средствDrug development & registration2305-20662658-5049LLC «CPHA»pharmjournal-412Research ArticleФАРМАЦЕВТИЧЕСКАЯ ТЕХНОЛОГИЯ И НАНОТЕХНОЛОГИИPHARMACEUTICAL TECHNOLOGY AND NANOTECHNOLOGYЖЕВАТЕЛЬНАЯ ЛЕКАРСТВЕННАЯ РЕЗИНКА КАК ПЕРСПЕКТИВНАЯ СИСТЕМА ДОСТАВКИ ЛЕКАРСТВ (ОБЗОР)MEDICINAL CHEWING GUM AS A PROMISING DRUG DELIVERY SYSTEM (REVIEW)СоловьёваН. Л.SolovievaN. L.noemail@neicon.ruСокуренкоМ. С.SokurenkoM. S.noemail@neicon.ruФГАОУ ВО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава РоссииI.M. Sechenov First Moscow State Medical UniversityФГБУН «ФИЦ питания и биотехнологии»Scientific Research Institute of Nutrition201709012019029095Copyright © Соловьёва Н.Л., Сокуренко М.С., 20192019Соловьёва Н.Л., Сокуренко М.С.Solovieva N.L., Sokurenko M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmjournal.ru/jour/article/view/412

Жевательные лекарственные резинки (ЖЛР) являются альтернативой твердым лекарственным формам для перорального применения. В Фармакопее США представлена статья на никотинсодержащую жевательную резинку. Монография этой лекарственной формы имеется в Белорусской и Европейской Фармакопеях. В статье представлен анализ литературы о применении ЖЛР в качестве системы доставки лекарств, о вспомогательных веществах для изготовления ЖЛР, а так же рассмотрены схемы производства лекарственных жевательных резинок и оценка их качества.

Medicated chewing gum (MCG) are an alternative to solid dosage forms for oral use. In the Pharmacopoeia of the United States submitted an article on chewing gum of nicotine. A monograph of this drug form is available in Belarusian and European Pharmacopoeias. The article presents the analysis of the literature on the use MCG as delivery system of drugs, excipients for the manufacture of MCG, as well as the schemes for the production of medicinal chewing gum and tests of their quality.

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The authors declare that there are no conflicts of interest present.