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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pharmjournal</journal-id><journal-title-group><journal-title xml:lang="ru">Разработка и регистрация лекарственных средств</journal-title><trans-title-group xml:lang="en"><trans-title>Drug development &amp; registration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2305-2066</issn><issn pub-type="epub">2658-5049</issn><publisher><publisher-name>LLC «CPHA»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pharmjournal-431</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИТИЧЕСКИЕ МЕТОДИКИ И МЕТОДЫ КОНТРОЛЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYTICAL AND QUALITY CONTROL METHODS</subject></subj-group></article-categories><title-group><article-title>ИССЛЕДОВАНИЕ АМИНОКИСЛОТНОГО ПРОФИЛЯ ZINGIBER OFFICINALE (ZINGIBERACEAE) МЕТОДАМИ ТОНКОСЛОЙНОЙ ХРОМАТОГРАФИИИ СПЕКТРОФОТОМЕТРИИ</article-title><trans-title-group xml:lang="en"><trans-title>INVESTIGATION OF AMINO ACID PROFILE ZINGIBER OFFICINALE (ZINGIBERACEAE) BY THE THIN LAYER CHROMATOGRAPHY AND SPECTROPHOTOMETRIC METHODS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савицкий</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Savitskiy</surname><given-names>N. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Легостева</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Legosteva</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургская государственная химико-фармацевтическая академия» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Saint-Petersburg State Chemical-Pharmaceutical Academy</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>09</day><month>01</month><year>2019</year></pub-date><volume>0</volume><issue>2</issue><fpage>208</fpage><lpage>212</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Савицкий Н.И., Легостева А.Б., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Савицкий Н.И., Легостева А.Б.</copyright-holder><copyright-holder xml:lang="en">Savitskiy N.I., Legosteva A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pharmjournal.ru/jour/article/view/431">https://www.pharmjournal.ru/jour/article/view/431</self-uri><abstract><p>Извлечения из корневищ имбиря (Zingiber officinale) широко применяются в производстве биологически активных добавок и в пищевой промышленности. В дополнение к эфирным маслам и фенольным соединениям имбирь также богат аминокислотами. Для идентификации аминокислотного профиля проведен качественный и количественный анализ корневищ имбиря. В результате проведенных экспериментов методом тонкослойной хроматографии идентифицированы следующие аминокислоты: аргинин, гистидин, глутаминовая кислота, изолейцин, валин, пролин, лейцин, метионин. Посредством спектрофотометрического анализа определено количество аминокислот - 10,22%. Относительная ошибка единичного определения с доверительной вероятностью 95% составляет 1,89%. Таким образом, можно сделать вывод о дальнейшем исследовании и совершенствовании подходов к стандартизации корневищ имбиря, а также создании новых лекарственных форм на его основе.</p></abstract><trans-abstract xml:lang="en"><p>Extracts from rhizomes of ginger (Zingiber officinale) are widely used in the production of biologically active additives and in the food industry. In addition to essential oils and phenolic compounds, ginger is also rich in amino acids. To identify the amino acid profile, a qualitative and quantitative analysis of the rhizomes of ginger was carried out. As a result of the experiments, the following amino acids were identified by thin-layer chromatography: arginine, histidine, glutamic acid, isoleucine, valine, proline, leucine, methionine. By means of spectrophotometric analysis, the number of amino acids was determined to be 10.22%. The relative error of the single definition with a confidence probability of 95% is 1.89%. Thus, we can conclude that further research and improvement of approaches to standardization of rhizomes of ginger, as well as the creation of new dosage forms based on it.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>корневище имбиря</kwd><kwd>аминокислоты</kwd><kwd>качественный анализ</kwd><kwd>тонкослойная хроматография</kwd><kwd>количественный анализ</kwd><kwd>спектрофотометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ginger rhizome</kwd><kwd>amino acids</kwd><kwd>qualitative analysis</kwd><kwd>thin layer chromatography</kwd><kwd>quantitative analysis</kwd><kwd>spectrophotometry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">B. Tepe, M. Sokmen, H.A. Akpulat, A. Sokmen. Screening of the antioxidant potentials of six Salvia species from Turkey // Food Chemistry. 2006. V. 95(2). P. 200-204.</mixed-citation><mixed-citation xml:lang="en">B. Tepe, M. 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