pharmjournalРазработка и регистрация лекарственных средствDrug development & registration2305-20662658-5049LLC «CPHA»pharmjournal-544Research ArticleФАРМАЦЕВТИЧЕСКАЯ ТЕХНОЛОГИЯ И НАНОТЕХНОЛОГИИPHARMACEUTICAL TECHNOLOGY AND NANOTECHNOLOGYТОКСИКОЛОГИЧЕСКИЕ И ФАРМАКОЛОГИЧЕСКИЕ ХАРАКТЕРИСТИКИ ВСПОМОГАТЕЛЬНЫХ ВЕЩЕСТВ ПРЕПАРАТОВ ТОРАСЕМИДАTOXICOLOGICAL AND PHARMACOLOGICAL CHARACTERISTICS OF EXCIPIENTS OF DRUG PRODUCTS OF TORASEMIDEИвкинД. Ю.IvkinD. Yu.noemail@neicon.ruТеслевА. А.TeslevA. A.noemail@neicon.ruДзюбаА. С.DziubaA. S.noemail@neicon.ruИвкинаА. С.IvkinaA. S.noemail@neicon.ruГБОУ ВО «Санкт-Петербургская государственная химико-фармацевтическая академия» Министерства здравоохранения Российской ФедерацииSt. Petersburg Chemical and Pharmaceutical AcademyАО «Фармпроект»JSC «Pharmproject»201809012019014652Copyright © Ивкин Д.Ю., Теслев А.А., Дзюба А.С., Ивкина А.С., 20192019Ивкин Д.Ю., Теслев А.А., Дзюба А.С., Ивкина А.С.Ivkin D.Y., Teslev A.A., Dziuba A.S., Ivkina A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmjournal.ru/jour/article/view/544

В статье представлены сведения о токсикологических и фармакологических характеристиках основных вспомогательных веществ, используемых при разработке препаратов торасемида (натрия кроскармеллозы, микрокристаллической целлюлозы, магния стеарата, крахмала кукурузного прежелатинизированного, кремния диоксида коллоидного, маннитола).

Information on the toxicological and pharmacological characteristics of the main excipients used in the formulation of torasemide (sodium croscarmellose, microcrystalline cellulose, magnesium stearate, pregelatinized corn starch, silica, mannitol) is presented in the article.

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The authors declare that there are no conflicts of interest present.