pharmjournalРазработка и регистрация лекарственных средствDrug development & registration2305-20662658-5049LLC «CPHA»10.33380/2305-2066-2021-10-1-97-105pharmjournal-886Research ArticleМЕТОДЫ АНАЛИЗА ЛЕКАРСТВЕННЫХ СРЕДСТВANALYTICAL METHODSИспользование подходов метаболомики в анализе лекарственных растений и фитопрепаратов (обзор)Use of Metabolomic Approaches in Analysis of Medicinal Plants and Phytopreparations (Review)https://orcid.org/0000-0002-7836-5785ОрловаА. А.OrlovaA. A.

197376, г. Санкт-Петербург, ул. Проф. Попова, д. 14, лит. А

Anastasiia A. Orlova

14A, Prof. Popov str., Saint-Petersburg, 197376

https://orcid.org/0000-0002-0816-2579СтругарЙ.StrugarJ.

197376, г. Санкт-Петербург, ул. Проф. Попова, д. 14, лит. А

Jovana Strugar

14A, Prof. Popov str., Saint-Petersburg, 197376

https://orcid.org/0000-0002-3656-4559ШтаркО. Ю.ShtarkO. Yu.

196608, г. Санкт-Петербург, Пушкин-8, шоссе Подбельского, д. 3

Oksana Yu. Shtark

3, Podbelsky chausse, Pushkin 8, Saint-Petersburg, 196608

https://orcid.org/0000-0002-2411-9191ЖуковВ. А.ZhukovV. A.

196608, г. Санкт-Петербург, Пушкин-8, шоссе Подбельского, д. 3

Vladimir A. Zhukov

3, Podbelsky chausse, Pushkin 8, Saint-Petersburg, 196608

https://orcid.org/0000-0002-6312-2027ЛужанинВ. Г.LuzhaninV. G.

197376, г. Санкт-Петербург, ул. Проф. Попова, д. 14, лит. А

Vladimir G. Luzhanin

14A, Prof. Popov str., Saint-Petersburg, 197376

https://orcid.org/0000-0002-7768-9059ПовыдышМ. Н.PovydyshM. N.

Повыдыш Мария Николаевна

197376, г. Санкт-Петербург, ул. Проф. Попова, д. 14, лит. А

Maria N. Povydysh

14A, Prof. Popov str., Saint-Petersburg, 197376

maria.povydysh@pharminnotech.comФГБОУ ВО «Санкт-Петербургский государственный химико-фармацевтический университет» Министерства здравоохранения Российской Федерации (ФГБОУ ВО СПХФУ Минздрава России)Saint-Petersburg State Chemical-Pharmaceutical UniversityФГБНУ «Всероссийский научно-исследовательский институт сельскохозяйственной микробиологии» (ФГБНУ ВНИИСХМ)Federal State Budgetary Scientific Institution «All-Russian Research Institute of Agricultural Microbiology RAS»20210102202110197105Copyright © Орлова А.А., Стругар Й., Штарк О.Ю., Жуков В.А., Лужанин В.Г., Повыдыш М.Н., 20212021Орлова А.А., Стругар Й., Штарк О.Ю., Жуков В.А., Лужанин В.Г., Повыдыш М.Н.Orlova A.A., Strugar J., Shtark O.Y., Zhukov V.A., Luzhanin V.G., Povydysh M.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pharmjournal.ru/jour/article/view/886Введение

Введение. Целью аналитического обзора является обобщение данных современной научной литературы о направлениях и возможностях использования подходов метаболомики в анализе лекарственных растений, растительного сырья и фитопрепаратов.

Текст

Текст. Анализ литературных данных показал, что метаболомные подходы имеют большой потенциал в области контроля качества многокомпонентных фитопрепаратов и биологически активных добавок (БАД), выявления фальсификаций редкого и дорогостоящего растительного сырья, хемосистематики лекарственных растений, изучении механизмов действия и токсичности лекарственных растений и т.д.

Заключение

Заключение. Метаболомный анализ может стать эффективной аналитической платформой, как для фитохимического исследования растительного сырья, так и для регулярных мероприятий по контролю качества растительного материала и фитопрепаратов.

Introduction

Introduction. The purpose of the analytical review is to summarize the data of modern scientific literature on the directions and possibilities of using the approaches of metabolomics in the analysis of medicinal plants, plant raw materials and herbal drugs.

Text

Text. Analysis of literature data showed that metabolomic approaches have great potential in the field of quality control of multicomponent phytopreparations and biologically active additives, detection of falsifications of rare and expensive plant materials, chemosystematics of medicinal plants, study of the mechanisms of action and toxicity of medicinal plants, etc.

Conclusion

Conclusion. Metabolic analysis can become an effective analytical platform both for phytochemical research of plant raw materials and for regular activities to control the quality of plant material and phytopreparations.

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The authors declare that there are no conflicts of interest present.