Development of a method of comparative analysis based on consumer properties of polymer compositions illustrated by adhesive plates

Introduction. Polymer compositions, which are the basis of most dosage forms intended for application to the skin, including transdermal patches, determine both the biopharmaceutical properties of the drug and the consumer properties of the dosage form. Consumer properties are important for the patient. They determine the patient's commitment not only to therapy, but also to a specific manufacturer. Adhesive plates of colostomy bags are used for fixing ostomy bags and protecting the skin of the peristomal area. They are characterized by a set of consumer properties that determine their quality and may be a good model for studying the influence of consumer properties on patient preferences.

Aim. Development of comparative analysis method of adhesive plates polymer compositions based on consumer properties.

Materials and methods. To achieve the research goal, a set of methods was used, including bibliographic, analytical, comparative, survey and structural-functional analysis. To determine the weighting coefficients of various consumer characteristics of adhesive plates, a survey of experts was conducted.

Results and discussion. The main consumer properties of adhesive plates of ostomy pouches have been determined, which include: no adhesive residue on the skin after removal, ease of removal, wearing time, flexibility, ease of use, resistance to moisture and secretions, comfort of use, adhesion, strength of adhesion to the skin, prevention of leakage and no peristomal complications. Based on expert evaluation, weighting coefficients for each consumer property were determined, and a methodology for comparative evaluation of adhesive plates of ostomy pouches was proposed. The methodology can be used for comparative analysis of adhesive plates from different manufacturers.

Conclusion. A methodology for the comparative evaluation of ostomy pouches was successfully developed. It can be used as a basis for developing a similar methodology for evaluating skin-applied dosage forms based on their consumer properties.

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