Development and Standardization of Crayons with Eucalimine
https://doi.org/10.33380/2305-2066-2020-9-4-99-106
Abstract
Introduction. Promising sources of preparation of antiinflammatory drugs of interest for practical medicine are substances of plant origin. One of them is eucalimine, isolated from leaves or shoots of eucalyptus prutoid (Eucalyptus viminalis Labil) of the myrtle family (Myrtaceae), is a purified sum of terpenoid phenoloaldehydes of the floroglucine series (euglobals) and triterpenoids.
Aim. The purpose of the present work is to create drug pencils with eucalimine for the prevention and treatment of inflammatory skin diseases.
Materials and methods. The object of research is eucalymin. The study of the shape and size of ekalimine particles and its distribution in various dispersion media: cetyl alcohol, stearyl alcohol, emulsion wax, castor oil, peach oil, medical petroleum jelly was carried out.
Results and discussion. The paper presents the results of experimental studies justifying the selection of adjuvants for medical pencils and their standardization.
Conclusion. The composition and technology of medicinal pencils with eucalimine for external use has been developed, quality indicators have been established.
About the Authors
K. Yu. Aleshnikova
All-Russian research Institute of medicinal and aromatic plants
Russian Federation
Russian Federation
Kristina Yu. Aleshnikova
7/1, Green str., Mosсow, 117216
V. N. Dul
All-Russian research Institute of medicinal and aromatic plants
Vyacheslav N. Dul
7/1, Green str., Mosсow, 117216
M. A. Dzhavakhyan
All-Russian research Institute of medicinal and aromatic plants
Marina A. Dzhavakhyan
7/1, Green str., Mosсow, 117216
O. A. Semkina
All-Russian research Institute of medicinal and aromatic plants
Olga A. Semkina
7/1, Green str., Mosсow, 117216
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Review
For citations:
Aleshnikova K.Yu., Dul V.N., Dzhavakhyan M.A., Semkina O.A. Development and Standardization of Crayons with Eucalimine. Drug development & registration. 2020;9(4):99-106. (In Russ.) https://doi.org/10.33380/2305-2066-2020-9-4-99-106
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