ВЛИЯНИЕ ГИДРОКСИЭТИЛЦЕЛЛЮЛОЗЫ НА ВЫСВОБОЖДЕНИЕ ГЛИБЕНКЛАМИДА ИЗ ТАБЛЕТОК ПРОЛОНГИРОВАННОГО ДЕЙСТВИЯ
Аннотация
Приведены практические результаты исследования влияния размера частиц и способа обработки активной субстанции глибенкламида на профиль высвобождения из матричной таблетированной формы пролонгированного действия. Изучено влияние гидроксиэтилцеллюлозы как компонента, используемого для пролонгации высвобождения, а так же как вещества, способного улучшать скорость рас творения и способствовать более полному высвобождению активной субстанции из пролонгированной готовой лекарственной формы.
Об авторе
С. В. Трофимов
Пятигорский медико-фармацевтический институт - филиал ГБОУ ВПО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации
Россия
Россия
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Рецензия
Для цитирования:
Трофимов С.В. ВЛИЯНИЕ ГИДРОКСИЭТИЛЦЕЛЛЮЛОЗЫ НА ВЫСВОБОЖДЕНИЕ ГЛИБЕНКЛАМИДА ИЗ ТАБЛЕТОК ПРОЛОНГИРОВАННОГО ДЕЙСТВИЯ. Разработка и регистрация лекарственных средств. 2016;(3):52-58.
For citation:
Trofimov S.V. EFFECT OF HYDROXYETHYLCELLULOSE ON THE RELEASE OF GLIBENCLAMIDE FROM SUSTAINED RELEASE TABLETS. Drug development & registration. 2016;(3):52-58. (In Russ.)
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