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Разработка и регистрация лекарственных средств

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ВЛИЯНИЕ ГИДРОКСИЭТИЛЦЕЛЛЮЛОЗЫ НА ВЫСВОБОЖДЕНИЕ ГЛИБЕНКЛАМИДА ИЗ ТАБЛЕТОК ПРОЛОНГИРОВАННОГО ДЕЙСТВИЯ

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Аннотация

Приведены практические результаты исследования влияния размера частиц и способа обработки активной субстанции глибенкламида на профиль высвобождения из матричной таблетированной формы пролонгированного действия. Изучено влияние гидроксиэтилцеллюлозы как компонента, используемого для пролонгации высвобождения, а так же как вещества, способного улучшать скорость рас творения и способствовать более полному высвобождению активной субстанции из пролонгированной готовой лекарственной формы.

Об авторе

С. В. Трофимов
Пятигорский медико-фармацевтический институт - филиал ГБОУ ВПО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации
Россия


Список литературы

1. K. Wu, J. Li. Formation and characterization of solid dispersions of piroxicam and polyvinylpyrrolidone using spray drying and precipitation with compressed antisolvent // Journal of pharmaceutical sciences. 2009. V. 98(7). P. 2422-2431.

2. S. Kumar, J. Shen, D.J. Burgess. Nano-amorphous spray dried powder to improve oral bioavailability of itraconazole // Journal of Controlled Release. 2014. V. 192. P. 95-102.

3. B. Chauhan, S. Shimpi, A. Padarkar. Preparation and evaluation of glibenclamide-polyglycolized glycerides solid dispersions with silicon dioxide by spray drying technique // European Journal of Pharmaceutical Sciences. 2005. V. 26(2). P. 219-230.

4. E. Gue, S. Muschert, J.F. Willart, F. Danede, M. Descamps, E. Delcourt-Debruyne, J. Siepmann. Accelerated fenofibrate release from spray-dried microparticles based on polymer blends // Journal of drug delivery science and technology. 2014. V. 24(2). P. 185-190.

5. J. Fu, L. Xu, X. Wang, S. Zhang, X. Tao, X. Zhao, H. He, X. Tang. Nimodipine (NM) tablets with high dissolution containing NM solid dispersions prepared by hot-melt extrusion // Drug Development and Industrial Pharmacy. 2011. V. 37(8). P. 934-944.

6. R.K. Rajeswari, K. Abbulu, M. Sudhakar. Development, characterization and solubility study of solid dispersion of Valsartan // Journal of Chemical and Pharmaceutical Research. 2014. V. 3(1). P. 180-187.

7. D.S. Johes, D.N. Margetson, M.S. McAllister, Y. Tao, S. Li, C.P. McCoy, G.P. Andrews. Thermodynamically stable amorphous drug dispersions in amorphous hydrophilic polymers engineered by hot melt extrusion // Chemical Engineering Research and Design. 2014. V. 92(12). P. 3046-3054.

8. P.C. Senapati, S.K. Sahoo, A.N. Sahu. Mixed surfactant based (SNEDDS) self-nanoemulsifying drug delivery system presenting efavirenz for enhancement of oral bioavailability // Biomedicine & Pharmacotherapy. 2016. V. 80. P. 42-51.

9. U. Paaver, V. Matto, P. Veski. Effect of non-ionic surfactants on the dissolution of poorly soluble drugs // European journal of pharmaceutical sciences. 2007. V. 32(1). P. 34-35.

10. C. Maderuelo, A. Zarzuelo, J. M. Lanao. Critical factors in the release of drugs from sustained release hydrophilic matrices // Journal of Controlled Release. 2011. V. 154. P. 2-19.

11. L. Yang, R. Fassihi. Examination of drug solubility, polymer types, hydrodynamics and loading dose on drug release behavior from a triple-layer asymmetric configuration delivery system // International Journal of Pharmaceutics. 1997. V. 155. P. 219-229.

12. S. Ensslin, K.P. Moll, K. Paulus, K. Mader. New insight into modified release pellets - Internal structure and drug release mechanism // Journal of Controlled Release. 2008. V. 128. P. 149-156.

13. S. Conti, L. Maggi, L. Segale, E. Ochoa Machiste, U. Conte, P. Grenier, G. Vergnault. Matrices containing NaCMC and HPMC. Swelling and release mechanism study// International Journal of Pharmaceutics 2007. V. 333. P. 143-151.

14. D.S. Roy, B.D. Rohera. Comparative evaluation of rate of hydration and matrix erosion of HEC and HPC and study of drug release from their matrices // European Journal of Pharmaceutical Sciences. 2002. V. 16. P. 193-199.

15. S. Yalkowsky, S.C. Valvani. Solubility and Partitioning. I: Solubility of Nonelectrolytes in Water // Journal of Pharmaceutical Sciences. 1980. V. 69(8). P. 912-922.

16. http://www.drugbank.ca/drugs/DB01016 (дата обращения 04.03.2016).

17. Analytical profiles of drug substances: Glibenclamide / Ed. by Klaus Florey. - New Jersey: Academic Press. 1981. 727 p.

18. Z.H. Loh, A.K. Samanta, P.W.S. Heng. Overview of milling techniques for improving the solubility of poorly water-soluble drugs // Asian journal of pharmaceutical sciences. 2015. V. 10. P. 255-274.

19. P. Khadka, J. Ro, H. Kim, I. Kim, J. T. Kim, Hyunil Kim, J.M. Cho, G. Yun, J. Lee. Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability // Asian journal of pharmaceutical sciences. 2014. V. 9. P. 304-316.

20. J. Lee, J.Y. Choi, C.H. Park. Characteristics of polymers enabling nano-comminution of water-insoluble drugs // International journal of pharmaceutics. 2008. V. 355. P. 328-336.

21. R. Chen, C. Yi, H. Wu, S. Guo. Degradation kinetics and molecular structure development of hydroxyethyl cellulose under the solid state mechanochemical treatment // Carbohydrate Polymers. 2010. V. 81. P. 188-195.

22. ОФС 1.4.1.0015.15. Таблетки // Государственная фармакопея Российской Федерации. 13-е изд. - М., 2015.

23. ОФС 1.4.2.0014.15. Растворение для твердых дозированных лекарственных форм // Государственная фармакопея Российской Федерации. 13-е изд. - М., 2015.

24. H. Liu, L.S. Taylor, K.J. Edgar. The role of polymers in oral bioavailability enhancement: a review // Polymer. 2015. V. 77. P. 399-415.

25. N.S. Abbas, M. Amin, M.A. Hussain, K.J. Edgar, M.N. Tahir, W. Tremel. Extended release and enhanced bioavailability of moxifloxacin conjugated with hydrophilic cellulose ethers // Carbohydrate Polymers. 2016. V. 136. P. 1297-1306.

26. W.H. De Jong, P.J.A. Borm. Drug delivery and nano- particles: Applications and hazards // International journal of nanomedicine. 2008. V. 3(2). P. 133-149.

27. K. Mitchell, J.L. Ford, D.J. Armstrong, P.N.C. Elliott, J.E. Hogan, C. Rostron. The influence of the particle size of hydroxypropylmethylcellulose K15M on its hydration and performance in matrix tablets // International Journal of Pharmaceutics, 1993. V. 100. P. 175-179.

28. P.W.S. Heng, L.W. Chan, M.G. Easterbrook, X. Li. Investigation of the influence of mean HPMC particle size and number of polymer particles on the release of aspirin from swellable hydrophilic matrix tablets // Journal of Controlled Release. 2001. V. 76. P. 39-49.

29. M.V. Velasco, J.L. Ford, P. Rowe, A.R. Rajabi-Siahboomi. Influence of drug: hydroxypropylmethylcellulose ratio, drug and polymer particle size and compression force on the release of diclofenac sodium from HPMC tablets // Journal of Controlled Release. 1999. V. 57. P. 75-85.

30. C. Eapen, V.G. Prasanth, A. Rai. Development of UV Spectrometric Method of Glibenclamide (Glyburide) in Bulk and Pharmaceutical Formulations // International Journal of ChemTech Research. 2012. V. 4(1). P. 356-360.

31. V.V. Karkhanis, A.D. Captain, P.H. Patel. Development and Validation of UV Spectrophotometric method for estimation of Glibenclamide in bulk and Pharmaceutical dosage forms // Journal of Pharmacy Research Biomed Rx. 2013. V. 1(1). P. 1-3.

32. НД 42-3120-05. Манинил 3,5 мг. 2005.

33. The Unired States Pharmacopeial Convention. USP 36 NF-31.2013.

34. E. Aparecida dos Santos Gianotto, R. Pires Arantes, M.J. Lara-Filho, A.C. Saraiva. Casimiro Filho, M.M. Fregonezi-Nery. Dissolution test for glibenclamide tablets // Quimica Nova. 2007. V. 30(5). P. 1218-1221.


Для цитирования:


Трофимов С.В. ВЛИЯНИЕ ГИДРОКСИЭТИЛЦЕЛЛЮЛОЗЫ НА ВЫСВОБОЖДЕНИЕ ГЛИБЕНКЛАМИДА ИЗ ТАБЛЕТОК ПРОЛОНГИРОВАННОГО ДЕЙСТВИЯ. Разработка и регистрация лекарственных средств. 2016;(3):52-58.

For citation:


Trofimov S.V. EFFECT OF HYDROXYETHYLCELLULOSE ON THE RELEASE OF GLIBENCLAMIDE FROM SUSTAINED RELEASE TABLETS. Drug development & registration. 2016;(3):52-58. (In Russ.)

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