FEATURES ENZYMATIC RELEASE BIOCOMPATIBLE MICROCAPSULES WITH BUILT-IN SHELL INHIBITOR PEPTIDASE
Abstract
Microcapsules consisted of biocompatible components- bovine serum albumin and tannic acid were made using Layer-by-Layer encapsulation method. Process of microcapsule formation was studied. Poly(allyl)amine hydrochloride (PAH) was included into the microcapsules and process of its release into medium with neutral and alkaline pH and trypsin was studied. The ability to control release of model substance PAH from these capsules with the help of trypsin was shown.
About the Authors
E. V. Popova
Federal State Unitary Enterprise Research Institute of Hygiene, Occupational and Human Ecology FMBA
Russian Federation
Russian Federation
P. P. Beltiukov
Federal State Unitary Enterprise Research Institute of Hygiene, Occupational and Human Ecology FMBA
Russian Federation
Russian Federation
V. A. Kuznetsov
Federal State Unitary Enterprise Research Institute of Hygiene, Occupational and Human Ecology FMBA
Russian Federation
Russian Federation
S. G. Petunov
Federal State Unitary Enterprise Research Institute of Hygiene, Occupational and Human Ecology FMBA
Russian Federation
Russian Federation
A. S. Radilov
Federal State Unitary Enterprise Research Institute of Hygiene, Occupational and Human Ecology FMBA
Russian Federation
Russian Federation
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Review
For citations:
Popova E.V., Beltiukov P.P., Kuznetsov V.A., Petunov S.G., Radilov A.S. FEATURES ENZYMATIC RELEASE BIOCOMPATIBLE MICROCAPSULES WITH BUILT-IN SHELL INHIBITOR PEPTIDASE. Drug development & registration. 2017;(1):52-57. (In Russ.)
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