СПОСОБЫ СТАБИЛИЗАЦИИ ЛЕКАРСТВЕННЫХ ВЕЩЕСТВ И ИХ МЕТАБОЛИТОВ В БИОЛОГИЧЕСКИХ ЖИДКОСТЯХ ПРИ БИОАНАЛИТИЧЕСКИХ ИССЛЕДОВАНИЯХ (ОБЗОР)
Аннотация
В статье рассмотрены основные способы предотвращения разложения химически нестабильных лекарственных веществ и их метаболитов в биологических жидкостях в процессе хранения после отбора у пациентов, что необходимо для точного количественного определения данных соединений.
Об авторах
И. И. Яичков
ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России
Россия
Россия
А. Л. Хохлов
ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России
Россия
Россия
Ю. А. Джурко
ООО «Квинта-Аналитика Ярославль»
Россия
Россия
Л. Н. Шитов
ООО «Квинта-Аналитика Ярославль»
Россия
Россия
А. А. Трубников
ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России
Россия
Россия
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Рецензия
Для цитирования:
Яичков И.И., Хохлов А.Л., Джурко Ю.А., Шитов Л.Н., Трубников А.А. СПОСОБЫ СТАБИЛИЗАЦИИ ЛЕКАРСТВЕННЫХ ВЕЩЕСТВ И ИХ МЕТАБОЛИТОВ В БИОЛОГИЧЕСКИХ ЖИДКОСТЯХ ПРИ БИОАНАЛИТИЧЕСКИХ ИССЛЕДОВАНИЯХ (ОБЗОР). Разработка и регистрация лекарственных средств. 2017;(2):246-250.
For citation:
Yaichkov I.I., Khokhlov A.L., Dzhurko Y.A., Shitov L.N., Trubnikov A.A. METHODS OF STABILIZATION OF DRUG SUBSTANCES AND THEIR METABOLITES IN BIOLOGICAL FLUIDS DURING BIOANALYTICAL STUDY (REVIEW). Drug development & registration. 2017;(2):246-250. (In Russ.)
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