MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS
Abstract
Morphological and physico-chemical properties of erythrocytes encapsulated by terpenoindol alkaloids (TIA) by nephelometry and osmotic resistance of erythrocytes in a medium with low concentrations of sodium chloride have been studied. Changes in the morphological and physico-chemical parameters of TIA-loaded erythrocyte carriers and freshly isolated erythrocytes have been studied. It was found that during the process of encapsulation of TIA by a modified hypotonic swelling method, the morphological and physicochemical parameters of erythrocytes change insignificantly in comparison with the control.
About the Authors
O. V. Trineeva
Voronezh State University
Russian Federation
Russian Federation
A. J. Halahakoon
Voronezh State University
Russian Federation
Russian Federation
A. I. Slivkin
Voronezh State University
Russian Federation
Russian Federation
E. E. Chupandina
Voronezh State University
Russian Federation
Russian Federation
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Review
For citations:
Trineeva O.V., Halahakoon A.J., Slivkin A.I., Chupandina E.E. MORPHOLOGICAL AND PHYSICO-CHEMICAL PROPERTIES OF ERYTHROCYTE CARRIERS INCAPULATED BY TERPINEINDOLICALK ALOIDS. Drug development & registration. 2018;(1):146-150. (In Russ.)
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