SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER
Abstract
Alkaline hydrolysis of amide carboxyethylalginic acid, obtained by alkylation of alginic acid with acrylamide was carried out. The synthesis of carboxyethylalginic acid, which was not described before in the literature, was carried out. Conditions for obtaining polyacid were studied. The reaction of its esterification was investigated. The effect of acid concentration, reaction time and degree of carboxyethylation of the polysaccharide on the degree of esterification and the yield of the target product were shown.
About the Authors
T. I. Taradeyko
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation
Russian Federation
M. V. Sidorova
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation
Russian Federation
A. A. Iozep
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation
Russian Federation
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Review
For citations:
Taradeyko T.I., Sidorova M.V., Iozep A.A. SYNTHESIS OF CARBOXYETHYLALGINIC ACID AND ITS ETHYL ETHER. Drug development & registration. 2018;(4):17-22. (In Russ.)
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