RESULTS OF PRECLINICAL SAFETY TESTING COMPARISON FOR IBUPROFEN DRUG PRODUCTS
Abstract
The article contains materials, methods and results of preclinical experimental test of acute toxicity of drugs «Ibuprofen», suspension for oral administration [for children], LP 001651 from 13.04.2012 and referent «Nurofen for children», suspension for oral administration, P N014745/01 from 22.08.2008. Ibuprofen preparations compared were found equivalent in acute toxicity studies. The work will be continued in order to prove the bioequivalence of the claimed preparations.
About the Authors
E. A. Sitnikova
CJSC «Ekolab»
Russian Federation
Russian Federation
S. G. Mardanly
State University of Humanities and Technology
Russian Federation
Russian Federation
E. P. Rogozhnikova
CJSC «Ekolab»;
State University of Humanities and Technology
Russian Federation
Russian Federation
References
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4. Federal law № 61 at 12.04.2010 «Аbout the address of drugs» (in Russian).
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Review
For citations:
Sitnikova E.A., Mardanly S.G., Rogozhnikova E.P. RESULTS OF PRECLINICAL SAFETY TESTING COMPARISON FOR IBUPROFEN DRUG PRODUCTS. Drug development & registration. 2018;(4):86-88. (In Russ.)
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