DEFINITION OF CYTOSTATIC EFFECT OF PROTARGOLUM SOLUTIONS IN DIFFERENT CONCENTRATIONS ON HUMAN DERMAL FIBROBLASTS
Abstract
This article presents the data on the effect of protargolum solutions in different concentrations on human dermal fibroblasts. For evaluation of the metabolic activity of the cells MTT-test was used. This test is based on the ability of NAD-H-adjective oxydoreductases to represent the amount of viable cells. It was determined, that the critical concentration of protargolum solution, responsible for inhibitory effect on fibroblasts proliferation is on the range 2 · 10-2 - 5 · 10-1 mg/ml.
About the Authors
N. V. Mescheryakova
Peoples' Friendship University of Russia;
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
E. B. Dashinimaev
Koltzov Institute of Developmental Biology, Russian Academy of Sciences;
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
A. I. Marakhova
Peoples' Friendship University of Russia
Russian Federation
Russian Federation
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Review
For citations:
Mescheryakova N.V., Dashinimaev E.B., Marakhova A.I. DEFINITION OF CYTOSTATIC EFFECT OF PROTARGOLUM SOLUTIONS IN DIFFERENT CONCENTRATIONS ON HUMAN DERMAL FIBROBLASTS. Drug development & registration. 2016;(4):180-182. (In Russ.)
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