Development and validation of HPLC-MS/MS technique for the quantitative determination of a new derivative of sydnonymine and its metabolites in rabbit plasma

N. S. Popov; D. A. Gavrilenko; M. S. Baranov; D. E. Kaurova; I. N. Myasnyanko; I. A. Solokha; V. Yu. Balabanyan

Drug development & registration
Razrabotka i registraciâ lekarstvennyh sredstv

ISSN 2305-2066 (Print)
ISSN 2658-5049 (Online)

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Popov N.S., Gavrilenko D.A., Baranov M.S., Kaurova D.E., Myasnyanko I.N., Solokha I.A., Balabanyan V.Yu. Development and validation of HPLC-MS/MS technique for the quantitative determination of a new derivative of sydnonymine and its metabolites in rabbit plasma. Drug development & registration. 2026;15(2):154-170. (In Russ.) https://doi.org/10.33380/2305-2066-2026-15-2-2164

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ISSN 2305-2066 (Print)
ISSN 2658-5049 (Online)

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About the Authors

N. S. Popov
Federal State Budgetary Educational Institution of Higher Education "Tver State Medical University" of the Ministry of Healthcare of the Russian Federation
Russian Federation

4, Sovetskaya str., Tver, 170100

D. A. Gavrilenko
Federal State Budgetary Educational Institution of Higher Education "Tver State Medical University" of the Ministry of Healthcare of the Russian Federation
Russian Federation

4, Sovetskaya str., Tver, 170100

M. S. Baranov
Federal State Autonomous Educational Institution of Higher Education "N. I. Pirogov Russian National Research Medical University" of the Ministry of Health of the Russian Federation (Pirogov Russian National Research Medical University); Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS)
Russian Federation

1, Ostrovityanova str., Moscow, 117513;
Building 1, 16/10, Miklukho-Maklaya str., intra-city territory of a federal city Konkovo, Moscow, 117997

D. E. Kaurova
Federal State Autonomous Educational Institution of Higher Education "N. I. Pirogov Russian National Research Medical University" of the Ministry of Health of the Russian Federation (Pirogov Russian National Research Medical University)
Russian Federation

1, Ostrovityanova str., Moscow, 117513

I. N. Myasnyanko
Federal State Autonomous Educational Institution of Higher Education "N. I. Pirogov Russian National Research Medical University" of the Ministry of Health of the Russian Federation (Pirogov Russian National Research Medical University); Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS)
Russian Federation

1, Ostrovityanova str., Moscow, 117513;
Building 1, 16/10, Miklukho-Maklaya str., intra-city territory of a federal city Konkovo, Moscow, 117997

I. A. Solokha
Tver Branch of Federal State-Financed Institution «Federal Centre for Animal Health» (FGBI «ARRIAH»)
Russian Federation

100, Shishkova str., Tver, 170007

V. Yu. Balabanyan
Federal State Autonomous Educational Institution of Higher Education "N. I. Pirogov Russian National Research Medical University" of the Ministry of Health of the Russian Federation (Pirogov Russian National Research Medical University)
Russian Federation

1, Ostrovityanova str., Moscow, 117513

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