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METABOLIC ACTIVITY STUDY IN PEOPLE WITH DRUG ALLERGY USING «COCKTAIL» PHENOTYPING METHOD

Abstract

Study of main CYP isoforms activity using «cocktail» method was conducted on patients suffered from drug allergy with different concurrent diseases in order to determine the presence of correlation between drug allergy appearance and changes in biotransformation activity.

About the Authors

E. A. Egorenkov
I.M. Sechenov First Moscow State Medical University; National Research Center Institute of Immunology Federal Medical Biological Agency of Russia
Russian Federation


V. V. Smirnov
I.M. Sechenov First Moscow State Medical University; National Research Center Institute of Immunology Federal Medical Biological Agency of Russia
Russian Federation


T. N. Myasnikova
National Ressearch Center Institute of Immunology Federal Medical Biological Agency of Russia
Russian Federation


T. S. Romanova
National Ressearch Center Institute of Immunology Federal Medical Biological Agency of Russia
Russian Federation


References

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Review

For citations:


Egorenkov E.A., Smirnov V.V., Myasnikova T.N., Romanova T.S. METABOLIC ACTIVITY STUDY IN PEOPLE WITH DRUG ALLERGY USING «COCKTAIL» PHENOTYPING METHOD. Drug development & registration. 2016;(3):170-172. (In Russ.)

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ISSN 2305-2066 (Print)
ISSN 2658-5049 (Online)