MODERN ISSUES OF ORGANIZING RADIO PHARM PREPARATIONS PRODUCTION BASED ON ⁶⁸GA
Abstract
Functional diagnostics method (scintigraphy), connected with injection of radioactive isotopes with further getting of 2-D image by emitting radiation detection, is widely used in medicine. Scintigraphic visualization of infections and inflammation with ⁶⁸Ga-citrate is powerful diagnostic instrument for patients with inflammation or infection disease. ⁶⁸Ga is short-lived positron emitting radionuclide (half-life time is 67,6 min, positron energy is 2,92 MeV). Such characteristics allowed to get better images of other radiopharmaceuticals with ⁶⁸Ga. Benefits of the drugs, mechanism of mother radionuclide fission is described in the article, as well as equipment for ⁶⁸Ga-citrate synthesis with all the technological processes. Obtained ⁶⁸Ga-citrate is suitable for positron emission tomography diagnostics for infection disease and inflammation detection in clinical practice.
About the Authors
O. A. Melnikova
Ural State Medical University
Russian Federation
Russian Federation
D. N. Muratov
LLC «PET-Technology»
Russian Federation
Russian Federation
A. F. Sitnikov
LLC «PET-Technology»
Russian Federation
Russian Federation
E. V. Shorikov
LLC «PET-Technology»
Russian Federation
Russian Federation
D. Yu. Kobesova
LLC «PET-Technology»
Russian Federation
Russian Federation
References
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Review
For citations:
Melnikova O.A., Muratov D.N., Sitnikov A.F., Shorikov E.V., Kobesova D.Yu. MODERN ISSUES OF ORGANIZING RADIO PHARM PREPARATIONS PRODUCTION BASED ON ⁶⁸GA. Drug development & registration. 2018;(1):134-136. (In Russ.)
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