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ANTIMICROBIAL ACTIVITY OF N-ARILIDENHYDRAZIDE OF CARBOXYETHYLALGINIC ACID

Abstract

The antibacterial and antifungal activity of the products of the interaction of hydrazides of carboxyethyl alginic acid with 5-nitrofurfurol and β-(5-nitro-2-furyl)-acrolein was studied. The effect of analytical studies on the test-culture of Staphylococcus aureus, Escherichia coli and Candida albicans. The test compounds showed antibacterial action comparable to the furacilin and high antifungal effect. Samples of acylhydrazones β-(5-nitro-2-furyl)-acrolein have high fungicidal and fungistatic activity.

About the Authors

D. N. Kosareva
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare of Russia
Russian Federation


T. I. Taradeyko
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare of Russia
Russian Federation


S. N. Galasheva
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare of Russia
Russian Federation


E. P. Ananieva
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare of Russia
Russian Federation


A. A. Iozep
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare of Russia
Russian Federation


References

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Review

For citations:


Kosareva D.N., Taradeyko T.I., Galasheva S.N., Ananieva E.P., Iozep A.A. ANTIMICROBIAL ACTIVITY OF N-ARILIDENHYDRAZIDE OF CARBOXYETHYLALGINIC ACID. Drug development & registration. 2018;(3):110-113. (In Russ.)

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ISSN 2305-2066 (Print)
ISSN 2658-5049 (Online)