STUDY OF SAPONINS IN ROOTS OF ACHYRANTHES BIDENTATA BLUME
Abstract
To study saponins from the roots of Achyranthes bidentata Blume (Amaranthaceae) were collected in Vietnam. Achyranthes bidentata is a tropical plant in the Amaranthaceae family, which is the most popularmedicinal plant in Asia. A complex of biologically active substances (BAS) was found in the roots of Achyranthes bidentata Blume that included saponins, ecdysteroids, polysaccharides, alkaloids, and coumarins. In this study, qualitative and quantitative analysis of saponins of Achyranthes roots was carried out. As a result of the studies, it was found that the roots contain at least three saponins predominantly triterpene group, which are derivatives of oleanolic acid. By spectrophotometric analysis of productsobtained as a result of the reaction of saponins with concentrated sulfuric acid, the quantity of the content of saponins was defined, equivalent to oleanolic acid is equaled 2,76±0,04%.
About the Authors
T. N. Nguyen
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare
Russian Federation
Russian Federation
M. G. Ozhigova
Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Healthcare
Russian Federation
Russian Federation
References
1. Xirui H. et al. The genus Achyranthes: A review on traditional uses, phytochemistry, and pharmacological activities // Journal of ethnopharmacology 2017. V. 203. Р. 260-278.
2. Cheng Qiong et al. Neurotrophic and neuroprotective actions of Achyranthes bidentata polypeptides on cultured dorsal root ganglia of rats and on crushed common peroneal nerve of rabbits // Neuroscience letters. 2014. № 562. Р. 7-12.
3. He Cui-Cui et al. Osteoprotective effect of extract from Achyranthes bidentata in ovariectomized rats // Journal of ethnopharmacology. 2010. V. 2. № 127. Р. 229-234.
4. P.U. Devi et al. Antibacterial, in vitrolipid peroxidation and phytochemical observation on Achyranthes bidentata Blume // Pakistan Journal of Nutrition. 2007. V. 6. № 5. Р. 447-451.
5. Li Z. K., Li D. D. The immunomodulatory effect of Achyranthes bidentata polysaccharides // Yao xue xue bao - Acta pharmaceutica Sinica. 1997. V. 12. №. 32. Р. 881-887.
6. Do Tat Loi. Những cây thuốc và vị thuốc Việt Nam // NxbY Hoc. 2004. Trang 48-49.
7. Вьетнамская фармакопея. IV из. 2010. C. 882.
8. Yanze L., Wang Z., Zhang J. Dietary Chinese Herbs. - Vienna: Springer. 2015. Р. 45-48.
9. Marouf А. et al. Triterpene saponins from the roots of Achyranthes bidentate // Pharmaceutical biology. 2001. V. 4. № 39. C. 263-267.
10. Wang L., Zhu Y., Liao M. Therapeutic effects of saponins from Achyranthes bidentata in SHRsp // Zhongguo Zhong yao za zhi - China journal of Chinese materia medica. 2011. V. 9. № 36. Р. 1239-1241.
11. Kovalev V. N., Popova N. V., Kislichenko V. S. i dr. Workshop on pharmacognosy / Under the Society. Ed. Kovalev V. N. - Kharkov: Publishing house of NfaU; Golden Pages. 2003. C. 512.
12. Fedoseeva L. M., Bashar D. B. The study of saponins in the underground organs of the ferul of Hermon // Chemistry of plant raw materials. 2016. № 1. S. 181-184.
13. Pisarev D. I. i dr. Saponins and their determination in the rhizomes of Manchurian aralia in the conditions of the Belgorod region // Chemistry of plant raw materials. 2009. № 4. S. 197-198.
Review
For citations:
Nguyen T.N., Ozhigova M.G. STUDY OF SAPONINS IN ROOTS OF ACHYRANTHES BIDENTATA BLUME. Drug development & registration. 2018;(3):148-151. (In Russ.)
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