DEVELOPMENT AND VALIDATION OF METHOD FOR POTENTIOMETRIC DETERMINATION OF SILVER IN PHARMACEUTICAL SUBSTANCE «ARGAMID»
Abstract
The article presents data on the development of an assay method of silver in pharmaceutical substance «Argamid» based on silver salt sulfadimidine. The method is based on the rhodanometric titration with potentiometric indication of the final point. The results of the validation assessment of the method are shown.
About the Authors
N. S. Skosyreva
Ural State Medical University, Ministry of Healthcare
Russian Federation
Russian Federation
N. A. Malakhova
Ural Federal University named after the first President of Russia B.N. Yeltsin
Russian Federation
Russian Federation
S. Y. Saraeva
Ural Federal University named after the first President of Russia B.N. Yeltsin
Russian Federation
Russian Federation
O. A. Melnikova
Ural State Medical University, Ministry of Healthcare
Russian Federation
Russian Federation
A. Y. Petrov
Ural State Medical University, Ministry of Healthcare
Russian Federation
Russian Federation
References
1. Правила составления, изложения и оформления стандартов качества на фармацевтические субстанции: Методические рекомендации. - М. 2009. 68 с.
2. Фармакопея США: USP 29; Национальный формуляр: NF24: в 2 т.: пер. с англ. Т. 1. - М.: ГЭОТАР-Медиа, 2009. 1720 с.
3. И.В. Пятницкий, В.В. Сухан. Аналитическая химия серебра. - М.: Наука. 1975. 264 с.
4. Государственная фармакопея Российской Федерации, XIII издание: в 3 т. - М.: ФЭМБ, 2015.
5. Валидация аналитических методик для производителей лекарств: Типовое руководство предприятия по производству лекарственных средств / Под ред. В.В. Береговых. - М.: Литерра, 2008. 132 с.
Review
For citations:
Skosyreva N.S., Malakhova N.A., Saraeva S.Y., Melnikova O.A., Petrov A.Y. DEVELOPMENT AND VALIDATION OF METHOD FOR POTENTIOMETRIC DETERMINATION OF SILVER IN PHARMACEUTICAL SUBSTANCE «ARGAMID». Drug development & registration. 2016;(4):106-110. (In Russ.)
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