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PRECLINICAL AND CLINICAL STUDIES

 
Issue Title
 
Online First Efficacy of exosomes in a chronic skin lesion model in vivo Abstract   PDF (Rus)
I. I. Glazko, E. A. Dubova, E. I. Balakin, O. V. Rukodayny, V. I. Pustovoit
 
Online First In vitro models for biological activity evaluation of a new antifibrotic drug based on the vesicular fraction of the human mesenchymal stromal cells secretome Abstract   PDF (Rus)
U. D. Dyachkova, N. A. Basalova, M. A. Vigovskiy, A. Yu. Efimenko, O. A. Grigorieva
 
Online First Automated quantitative analysis of coat and skin coloration in laboratory animals Abstract   PDF (Rus)
V. A. Prikhodko, U. V. Nogaeva, D. Yu. Ivkin, S. V. Okovityi
 
Online First Effect of different doses of paricalcitol on the expression of vitamin D receptors in mice liver tissue Abstract   PDF (Rus)
T. P. Sataieva, V. Yu. Malygina, A. A. Davydova, M. A. Kriventsov, A. K. Gurtovaya
 
Online First Effects of glycyrrhizinic acid on neuromotor function in leptin-resistant mice Abstract   PDF (Rus)
T. M. Matuzok, V. A. Prikhodko, S. M. Napalkova, O. V. Buyuklinskaya, S. V. Okovityi
 
Vol 14, No 2 (2025) The excretion study of a new derivative of 4,5-dihydroisoxazole-5-carboxamide Abstract   PDF (Rus)
I. I. Yaichkov, M. K. Korsakov, N. N. Volkhin, V. E. Zaykova, O. E. Lasaraynz
 
Vol 14, No 2 (2025) Analysis of the features of planning bioequivalence studies with adaptive design for drug products analogous to endogenous compounds ademetionine Abstract   PDF (Rus)
N. N. Eremenko
 
Vol 14, No 2 (2025) Evaluation of psychotropic effects of a novel chromone-containing allylmorpholine derivative in BALB/c mice Abstract   PDF (Rus)
M. M. Puchik, D. D. Shitc, Yu. I. Sysoev, N. M. Chernov, I. A. Titovich, S. V. Okovityi
 
Vol 14, No 2 (2025) Study of the biostimulating effect of a decoction of Michurin's chokerenia leaves in vitro using the Parameсium caudatum cilia test system Abstract   PDF (Rus)
O. V. Pugacheva, A. V. Buzlama, A. Yu. Kuznetsov, O. V. Trineeva
 
Vol 14, No 1 (2025) Comparison of the effects of copper chlorophyllin, riboxin, indralin and the combined use of glutathione and ascorbic acid on the survival of mice during fractionated X-ray irradiation Abstract   PDF (Rus)
L. A. Romodin, A. A. Moskovskij, O. V. Nikitenko, T. M. Bychkova, E. D. Rodionova
 
Vol 14, No 1 (2025) Correction of depressive-like state in rats induced by social stress using a new 3-substituted thietane-1,1-dioxide derivative Abstract   PDF (Rus)
G. G. Gaisina, I. L. Nikitina, E. E. Klen, R. A. Karaguzin, A. V. Samorodov
 
Vol 14, No 1 (2025) Comparative efficacy study of experimental chronic heart failure Abstract   PDF (Rus)
D. Yu. Ivkin, A. B. Zelentsova, M. V. Krasnova, A. A. Karpov, V. V. Pazheltsev, S. M. Napalkova, I. I. Terninko, I. A. Titovich, S. V. Okovitiy
 
Vol 14, No 1 (2025) Use of an electrical stimulation-induced fatigue protocol to evaluate the myotropic effects of metabolic-active agents in db/db mice Abstract   PDF (Rus)
V. A. Prikhodko, T. M. Matuzok, A. Yu. Grishina, V. E. Kovanskov, Yu. I. Sysoev, M. V. Titova, E. V. Popova, A. M. Nosov, D. Yu. Ivkin, S. V. Okovityi
 
Vol 14, No 1 (2025) Experimental murine non-alcoholic steatohepatitis is associated with behavioural, cognitive, and peripheral neuronal dysfunction Abstract   PDF (Eng)
V. A. Prikhodko, D. A. Orlyakhina, V. D. Petrova, V. E. Karev, D. Yu. Ivkin, S. M. Napalkova, S. V. Okovityi
 
Vol 14, No 1 (2025) Evaluation of the efficacy and safety of cytoflavin as a neuroprotector based on a systematic review Abstract   PDF (Rus)
E. K. Krasova, I. A. Titovich, K. O. Sidorov, S. V. Okovityi
 
Vol 13, No 4 (2024) Phase I pharmacokinetic study of etmaben, a malonic acid derivative Abstract   PDF (Rus)
P. K. Karnakova, K. K. Karnakova, T. N. Komarov, N. S. Bagaevа, M. O. Popova, D. Yu. Ivkin, O. A. Archakova, I. E. Shohin, I. A. Narkevich
 
Vol 13, No 4 (2024) Antifungal activity of thiadiazole derivative in experimental candidiasis in mice Abstract   PDF (Rus)
D. Yu. Ivkin, A. V. Karavaeva, T. F. Chernykh, M. V. Krasnova
 
Vol 13, No 4 (2024) Pharmacokinetic study of a new 4,5-dihydroisoxazole-5-carboxamide derivative in rats Abstract   PDF (Rus)
I. I. Yaichkov, M. K. Korsakov, N. N. Volkhin, S. S. Petukhov, A. N. Tyushina, V. E. Zaykova, O. E. Lasaraynz
 
Vol 13, No 4 (2024) Influence of saponin tauroside Sx1 on lifespan and expression of vitamin D receptors in the liver tissue of mice with influenza infection Abstract   PDF (Rus)
T. P. Sataieva, V. Yu. Maligina, T. P. Makalish, M. A. Kriventsov, A. K. Gurtovaya
 
Vol 13, No 4 (2024) The effect of the keto diet on lipid profile with type two diabetic patients Abstract   PDF (Eng)
Fadwa Ghassan, Ateka Mohammed, Zainab Kazim
 
Vol 13, No 4 (2024) Possible mechanism of effect of the empagliflozin on cardiovascular mortality Abstract   PDF (Eng)
A. V. Karpushev, M. V. Krasnova, D. Yu. Ivkin, V. B. Mikhailova, E. S. Klimenko, S. V. Okovityi, A. N. Kulikov
 
Vol 13, No 4 (2024) Cross-validation of methods for the quantitative determination of phenazepam and its active metabolite in human blood plasma at various extractions Abstract   PDF (Rus)
A. I. Platova, I. I. Kuzmin, D. V. Ivaschenko, I. I. Miroshnichenko
 
Vol 13, No 4 (2024) Pharmacokinetics of a new drug based on polysaccharide from acorus calamus in an experiment on laboratory animals Abstract   PDF (Rus)
S. V. Krivoshchekov, E. A. Yanovskaya, R. V. Gurto, O. S. Bryushinina, D. A. Isakov, A. V. Zykova, Yu. G. Zyuz’kova, A. M. Guryev, V. V. Udut, M. V. Belousov
 
Vol 13, No 3 (2024) PRT to predict pharmacokinetic profiles as part of a bioequivalence study of the drug deferasirox Abstract   PDF (Rus)   PDF (Eng)
A. V. Suvorova, P. A. Losenkova, Yu. V. Medvedev, E. A. Malashenko, I. E. Makarenko, A. M. Poluyanov, I. E. Shohin
 
Vol 13, No 3 (2024) Application of in vitro studies to predict the pharmacokinetics of rivaroxaban tablets Abstract   PDF (Rus)   PDF (Eng)
A. V. Suvorova, P. A. Losenkova, Yu. V. Medvedev, E. A. Malashenko, K. K. Karnakova, N. S. Bagaeva, A. Yu. Savchenko, A. M. Poluyanov, I. E. Shohin
 
Vol 13, No 3 (2024) Development and validation of the method of quantification of 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide and its metabolites in laboratory animal plasma Abstract   PDF (Rus)
I. I. Yaichkov, M. K. Korsakov, A. A. Shetnev, N. N. Volkhin, S. S. Petukhov
 
Vol 13, No 3 (2024) The role of doxorubicin in the formation of cardiotoxicity is a consensus statement. Part II. Cardiotoxicity of doxorubicin unrelated to myocytes and cardioprotection strategy (review) Abstract   PDF (Rus)
D. A. Andreev, E. I. Balakin, A. S. Samoilov, V. I. Pustovoit
 
Vol 13, No 3 (2024) Approaches to conducting a physiologically relevant test (PRT) in the study of medicines containing substance IIc of the BCS subclass using sorafenib as an example Abstract   PDF (Rus)   PDF (Eng)
A. V. Suvorova, Yu. V. Medvedev, P. A. Losenkova, O. S. Kramarenko, E. A. Malashenko, A. M. Poluyanov, I. E. Shohin
 
Vol 13, No 3 (2024) Quantitative determination of phenazepam and its active metabolite in human blood plasma at different extraction procedures Abstract   PDF (Rus)
I. I. Miroshnichenko, A. I. Platova, I. I. Kuzmin, D. V. Ivaschenko
 
Vol 13, No 3 (2024) Performing a physiologically relevant test for cladribine tablets Abstract   PDF (Rus)   PDF (Eng)
P. A. Losenkova, D. D. Gvozdev, A. V. Suvorova, Yu. V. Medvedev, V. S. Shcherbakova, Yu. G. Kazaishvili, K. Ya. Zaslavskaya, A. M. Poluyanov, I. E. Shohin
 
Vol 13, No 3 (2024) A biorelevant test for tablets glycine sublingual in the «simulated saliva» dissolution medium Abstract   PDF (Rus)   PDF (Eng)
S. D. Kulikova, М. B. Sokol, Z. M. Kozlova, P. A. Losenkova, P. Ya. Parshinova, A. M. Poluyanov
 
Vol 13, No 2 (2024) In vitro influence on fibrinolysis parameters of aqueous extracts of mushrooms growing on woody plants Abstract   PDF (Rus)
N. M. Faustova, D. N. Vedernikov, V. V. Bakanov, E. N. Pavlova, E. N. Vlasova, Yu. A. Skorik
 
Vol 13, No 2 (2024) Development and validation of a high-performance liquid chromatography with tandem mass spectrometry method for quantification of tofacitinib in human plasma Abstract   PDF (Eng)
E. S. Vetrova, P. K. Karnakova, N. S. Bagaeva, K. K. Karnakova, M. O. Popova, A. A. Popova, O. A. Archakova, T. N. Komarov, I. E. Shohin
 
Vol 13, No 2 (2024) The study of the influence of Thlaspi arvense L. on the characteristics of the reproductive system of male rats Abstract   PDF (Rus)   PDF (Eng)
R. G. Farkhutdinov, K. A. Pupykina, L. A. Sharafutdinova, A. M. Fedorova, Z. R. Hismatullina, M. I. Garipova, E. F. Koroleva, A. A. Yamaleeva, T. D. Rendyuk
 
Vol 13, No 2 (2024) Pharmacological screening of a new valproic acid derivative using the pharmacoencephalography method in rats Abstract   PDF (Rus)
Yu. I. Sysoev, D. D. Shits, M. M. Puchik, T. A. Gutiy, E. V. Fedorova, V. A. Prikhodko, I. A. Titovich, A. S. Melekhova, A. Ya. Bespalov, I. S. Knyazeva, E. B. Shustov, S. V. Okovityi
 
Vol 13, No 2 (2024) Validation of an enzyme-linked immunosorbent assay test-system for bevacizumab concentration determing in biological fluids Abstract   PDF (Rus)
V. V. Pisarev, A. V. Ivanov
 
Vol 13, No 2 (2024) HPLC-MS/MS method development and validation for the determination of tetradecapeptide in human plasma Abstract   PDF (Rus)
M. A. Tokareva, E. S. Melnikov, M. V. Belova, E. N. Fisher, T. A. Rodina, I. E. Shohin
 
Vol 13, No 1 (2024) Development and Validation of an HPLC-MS/MS Method for the Quantitative Determination of Etmaben in Human Blood Plasma Abstract   PDF (Rus)
P. K. Karnakova, T. N. Komarov, O. A. Archakova, D. Yu. Ivkin, E. S. Vetrova, I. I. Terninko, I. E. Shohin, I. A. Narkevich
 
Vol 13, No 1 (2024) Phase I Pharmacokinetics Study of Drug Areplivir® Zinc (INN: Favipiravir + Zinc Gluconate) (LLC "PROMOMED RUS", Russia) Abstract   PDF (Rus)
T. N. Komarov, N. S. Bagaeva, K. K. Karnakova, O. A. Archakova, D. S. Shchelgacheva, V. S. Shcherbakova, K. Ya. Zaslavskaya, P. A. Bely, A. V. Taganov, I. E. Shohin
 
Vol 13, No 1 (2024) Reciprocal Impact of Molnupiravir and Favipiravir Monocomponents of the Combination Drug on Each Other's Pharmacokinetics in a Phase I Clinical Trial Abstract   PDF (Rus)   PDF (Eng)
T. N. Komarov, K. K. Karnakova, N. S. Bagaeva, O. A. Archakova, M. O. Popova, V. S. Shcherbakova, K. Ya. Zaslavskaya, P. A. Bely, I. E. Shohin
 
Vol 13, No 1 (2024) Experimental Validation a Method for Assessing Neutralizing Antibodies of Romiplostim in Human Plasma Abstract   PDF (Rus)
A. N. Afanaseva, V. B. Saparova, I. E. Makarenko, T. A. Selmenskikh, D. V. Kurkin, A. L. Hohlov, R. V. Drai
 
Vol 13, No 1 (2024) Development and Validation of the Cell-based Functional Method for Neutralizing Anti-adalimumab Antibodies Detection in Human Serum Abstract   PDF (Rus)   PDF (Eng)
M. A. Nikiforova, I. A. Valouev, A. V. Petrov, E. E. Beketov, I. E. Shokhin
 
Vol 13, No 1 (2024) Development and Validation of an HPLC-MS/MS Method for Quantification of Apixaban in Human Plasma Abstract   PDF (Rus)   PDF (Eng)
U. D. Filonova, P. K. Karnakova, K. K. Karnakova, M. O. Popova, A. A. Popova, O. A. Archakova, T. N. Komarov, I. E. Shohin
 
Vol 13, No 1 (2024) Phase I Pharmacokinetics Study of Oral Administration of Esperavir® (INN: Molnupiravir) (LLC "PROMOMED RUS", Russia) Abstract   PDF (Rus)
T. N. Komarov, N. S. Bagaeva, K. K. Karnakova, K. Ya. Zaslavskaya, P. A. Bely, I. E. Shohin
 
Vol 13, No 1 (2024) Results of Preclinical Studies of 4-(2-(4-nitrophenyl)-2-oxoethyl)-1-(thietane-3-yl)-1H-1,2,4-triazole-4-th Bromide in Relation to the Hemostasis System in vivo Abstract   PDF (Eng)
Y. Wang, N. R. Bulatova, E. E. Klen, G. A. Rozit, I. L. Nikitina, E. A. Smolyarchuk, K. A. Zavadich, I. D. Krylova, A. V. Samorodov
 
Vol 13, No 1 (2024) Comparative Evaluation of the Diuretic Activity of Infusions of Four Species of the Genus Astragalus (Astragalus L.) in the Experiment Abstract   PDF (Rus)
U. A. Matvienko, A. Yu. Karetnikova, N. A. Durnova
 
Vol 13, No 1 (2024) The Role of Doxorubicin in the Formation of Cardiotoxicity – Generally Accepted Statement. Part I. Prevalence and Mechanisms of Formation (Review) Abstract   PDF (Rus)
D. A. Andreev, E. I. Balakin, A. S. Samoilov, V. I. Pustovoit
 
Vol 13, No 1 (2024) Biomarkers of Brain Ischemia (Review) Abstract   PDF (Rus)
A. S. Samoylov, E. I. Balakin, V. I. Pustovoit
 
Vol 13, No 1 (2024) Antibacterial and Chemical Properties of Sr-BDC Metal-Organic Framework (MOF) Abstract   PDF (Eng)
A. A. Vodyashkin, P. Kezimana, J. A. А. Mbarga, M. Y. Putirskaya, Ya. M. Stanishevskiy
 
Vol 12, No 4 (2023): Supplement 1 Assessment of Antihypoxic Activity of S-analoges of Dihydropyrimidin-2-ones and Their Condensed Derivatives Abstract   PDF (Rus)
N. A. Buzmakova, T. M. Zamaraeva, D. Yu. Ivkin, D. Yu. Apushkin, N. V. Slepova, N. V. Dozmorova
 
Vol 12, No 4 (2023): Supplement 1 Biological Activity study of the Melampyrum sylvaticum Extract Abstract   PDF (Rus)
E. E. Galishevskaya, E. N. Polyakova, T. V. Bombela, A. V. Agafontseva, A. G. Anisimova, O. A. Krotkova, T. A. Yagontseva, V. G. Luzhanin, E. R. Kurbatov
 
Vol 12, No 4 (2023): Supplement 1 Hepatoprotective Activity of Pine cones Extract Abstract   PDF (Rus)
D. K. Gulyaev, S. S. Zykova, V. D. Belonogova, D. O. Semakin, N. A. Buzmakova
 
Vol 12, No 4 (2023): Supplement 1 Evaluation of the Antioxidant Properties and Cytotoxic Activity of 1,3-dioxolane Derivatives Imidazole Abstract   PDF (Rus)
S. S. Zykova, M. V. Shustov, V. S. Talismanov
 
Vol 12, No 4 (2023): Supplement 1 Evaluation of New Derivatives of 2,4-dioxobutanoic Acid Salts in Behavioral Studies of Laboratory Animals Abstract   PDF (Rus)
A. I. Krasnova, V. D. Polezhaeva, N. A. Pulina
 
Vol 12, No 4 (2023): Supplement 1 Study of the Anti-inflammatory Activity of 2-hydroxy-4-oxo-4-R-2-butenoates of Heterylammonium, which Have an Effect on the Blood Clotting System Abstract   PDF (Rus)
F. V. Sobin, N. A. Pulina, S. V. Chashchina, A. V. Starkova, I. P. Rudakova, N. A. Buzmakova
 
Vol 12, No 4 (2023): Supplement 1 The Effect of New Water-soluble 2-aminoheteryl-3-ium 4-(het)aryl-2-hydroxy-4-oxobut-2-enoates on the Hemostasis System In vitro Abstract   PDF (Rus)
A. V. Starkova, F. V. Sobin, I. P. Rudakova, N. A. Pulina, N. V. Dozmorova, V. G. Luzhanin
 
Vol 12, No 4 (2023) Choleotropic Activity of Cistus salviifolius Extract Abstract   PDF (Rus)
E. D. Semivelichenko, A. S. Ivkina, A. V. Karavaeva, A. Yu. Grishina, E. I. Eletskaya, M. V. Krasnova, K. O. Sidorov, I. A. Titovich, D. Yu. Ivkin
 
Vol 12, No 4 (2023) Evaluation of the α2-adrenergic Agonist Mafedine Effects on White Outbred Mouse Behaviour Following Acute Administration Abstract   PDF (Rus)
N. S. Kurmazov, S. A. Chervonetskiy, V. A. Prikhodko, Yu. I. Sysoev, S. V. Okovityi
 
Vol 12, No 4 (2023) Flavonoids from Impatiens grandulifera and Their Antioxidant Activity Abstract   PDF (Rus)
A. K. Whaley, R. I. Lukashov, A. O. Whaley, E. V. Zhokhova, N. S. Gurina, M. U. Goncharov, G. P. Yakovlev, V. A. Tsiarletskaya
 
Vol 12, No 4 (2023) Neuroprotective Activity of 5-ethoxy-2-ethylthiobenzimidazole (Etomerzol) and 2-ethylthiobenzimidazole (Bemitil) in a Model of Middle Cerebral Artery Occlusion Abstract   PDF (Rus)
E. Yu. Zavarina, E. K. Krasova, I. A. Titovich, A. N. Kimaev
 
Vol 12, No 3 (2023) Pharmacological Activity of Sea Buckthorn Leaves: In silico and In vivo Abstract   PDF (Rus)
N. A. Kovaleva, O. V. Trineeva, A. V. Buzlama, A. Yu. Kuznetsov
 
Vol 12, No 3 (2023) Evaluation of the Antistaphylococcal Activity of the Pyrimidine Derivative Abstract   PDF (Rus)
A. A. Tsibizova, A. L. Yasenyavskaya, I. N. Tyurenkov, A. A. Ozerov, O. A. Baskina, M. A. Samotrueva
 
Vol 12, No 3 (2023) Examination of Elemental Composition of Herbal Medicinal Raw Materials of Voronezh Region Abstract   PDF (Rus)
N. A. Dyakova
 
Vol 12, No 3 (2023) Improvement of Myocardial Structure after Developed Fibrous Degeneration Under the Use of Allogenic Biomaterial Abstract   PDF (Rus)
A. I. Lebedeva, S. A. Afanasiev, E. M. Gareev, D. S. Kondratieva, L. A. Musina, S. V. Popov, A. V. Prusakov, A. V. Yashin, V. S. Ponamarev, V. D. Radnatarov
 
Vol 12, No 3 (2023) Antiarrhythmic Activity of Amino Acids Containing Nibentan Derivatives in Case of Symptoms of Occlusive and Reperfusion Arrhythmias Abstract   PDF (Rus)
S. M. Napalkova, O. V. Buyuclinskaya
 
Vol 12, No 3 (2023) An Open-label Randomized Crossover Study with Adaptive Design of the Pharmacokinetics and Bioequivalence of GP30121 and Ceraxon® Corrected for Endogenous Analyte Level Abstract   PDF (Rus)   PDF (Eng)
A. N. Arevefa, A. R. Dorotenko, S. M. Noskov, I. E. Makarenko, R. V. Drai, T. N. Komarov, O. A. Archakova, N. S. Bagaeva, I. E. Shokhin
 
Vol 12, No 3 (2023) Determination of Favipiravir in Human Blood Plasma by HPLC-MS/MS Abstract   PDF (Rus)   PDF (Eng)
T. N. Komarov, P. A. Karpova, O. A. Archakova, D. S. Shchelgacheva, P. K. Karnakova, N. S. Bagaeva, K. Ya. Zaslavskaya, P. A. Bely, I. E. Shohin
 
Vol 12, No 3 (2023) A Double-blind Randomized Comparative Phase I Study to Assess Biosimilarity and Immunogenicity of "Trastuzumab" (LLC "Mabscale", Russia) and Herceptin® (F. Hoffmann-La Roche Ltd., Switzerland) in Healthy Volunteers Abstract   PDF (Rus)
M. A. Kolganova, E. E. Beketov, V. V. Pisarev, A. V. Ivanov, S. V. Vasiliev, I. E. Shokhin
 
Vol 12, No 3 (2023) Antibacterial Activity of Essential Oils of Thymus serpyllum L. and Thymus marschallianus Willd. Abstract   PDF (Rus)
O. G. Shapoval, A. S. Sheremetyeva, N. A. Durnova, N. Q. Mukhamadiev, G. T. Rabbimova, M. K. Nazirbekov, M. A. Kupryashina
 
Vol 12, No 3 (2023) Patterns of Patient Recruitment in Clinical Studies on the Example of International Multicenter Clinical Studies (IMCTs) Abstract   PDF (Rus)
S. S. Milovanov
 
Vol 12, No 3 (2023) Innervation of Facial Muscles Using an Allogeneic Biomaterial in an Experiment Abstract   PDF (Eng)
L. A. Musina, O. R. Shangina, A. I. Lebedeva, A. V. Prusakov, A. V. Yashin, V. S. Ponamarev, V. D. Radnatarov, A. M. Lunegov
 
Vol 12, No 2 (2023) Hypertonic Activity of Injection Solutions Can Cause Post-injection Complications (Review) Abstract   PDF (Rus)
A. L. Urakov, N. A. Urakova, Z. V. Shubina, L. V. Lovtsova, A. V. Samorodov, K. G. Gurevich, A. P. Stolyarenko, V. I. Korunas, D. O. Lipatov, D. D. Muminov
 
Vol 12, No 2 (2023) Effect of a Farnesoid X-receptor Agonist on Postprandial Lipemia in Rats Fed a Supraphysiological Fat Dozes Abstract   PDF (Rus)
Yu. N. Alekhin, O. S. Popova, V. S. Ponamarev, P. A. Parshin
 
Vol 12, No 2 (2023) Study of the Radiosensitizing Action of Lithium Ascorbate Under Neutron and Photon Irradiation of Tumor Cells Abstract   PDF (Rus)
M. S. Tretyakova, A. G. Drozd, M. V. Belousov, K. S. Brazovskiy, M. S. Larkina, S. V. Krivoshchekov, A. A. Artamonov, I. A. Miloichikova, A. V. Bezmaga, A. M. Bolshakov, E. S. Sukhikh, E. V. Plotnikov
 
Vol 12, No 2 (2023) Development and Validation of the ELISA Method for Neutralizing Anti-trastuzumab Antibodies Detection in Human Blood Serum Abstract   PDF (Rus)   PDF (Eng)
M. A. Kolganova, O. S. Sagimbaeva, Ju. S. Borisova, E. E. Beketov, I. E. Shokhin
 
Vol 12, No 2 (2023) Simultaneous Determination of Nirmatrelvir and Ritonavir in Human Plasma by HPLC-MS/MS Abstract   PDF (Rus)   PDF (Eng)
T. N. Komarov, P. K. Karnakova, O. A. Archakova, D. S. Shchelgacheva, N. S. Bagaeva, I. E. Shohin, K. Ya. Zaslavskaya, P. A. Bely
 
Vol 12, No 2 (2023) Phase I Pharmacokinetics Study of Drug for Infusion «Areplivir» (INN: Favipiravir) (LLC "PROMOMED RUS", Russia) Abstract   PDF (Rus)
T. N. Komarov, N. S. Bagaeva, K. K. Karnakova, I. E. Shohin, K. Ya. Zaslavskaya, P. A. Bely
 
Vol 12, No 2 (2023) The Interconnection Between Pharmaceutical Development and Preclinical Research (Review) Abstract   PDF (Rus)
I. N. Ampilogova, M. V. Karlina, V. G. Makarov, M. N. Makarova
 
Vol 12, No 1 (2023) Pharmacokinetic and Bioequivalence Study of the Two-component Drug Product "Ezetimibe + rosuvastatin" (JSC "Sanofi-aventis group", Russia): Resuts and Experience with the Use of Enzymatic Hydrolysis in the Analysis of Samples Abstract   PDF (Rus)
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva
 
Vol 12, No 1 (2023) Preclinical Evaluation of a New Anti-COVID-19 Intravenous Immunoglobulin Abstract   PDF (Rus)
A. M. Nikolaeva, A. V. Ivanov, T. I. Smolyanova, M. V. Razumikhin, O. V. Belyakova, E. G. Shilova, N. R. Selezneva, T. V. Vyaznikova, A. I. Semicheva, E. I. Sakanyan
 
Vol 12, No 1 (2023) Behavioral Pharmacology as the Main Approach to Study the Efficiency of Potential Psychotropic Drugs: Analysis of Modern Methods (Review) Abstract   PDF (Rus)
I. I. Semina, A. Z. Baichurina, D. O. Nikitin, A. V. Nikitina, R. I. Moustafine, V. V. Khutoryanskiy
 
Vol 12, No 1 (2023) Old Drugs, New Indications (Review) Abstract   PDF (Rus)
I. I. Miroshnichenko, E. A. Valdman, I. I. Kuz'min
 
Vol 12, No 1 (2023) Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Analysis of Riluzole in Human Plasma and Its Application on a Bioequivalence Study Abstract   PDF (Eng)
S. Mohammadzadeh, F. Salmannejad, M. Mohammadzadeh, T. Ghari, S. Sadrai, J. Zaringhalam
 
Vol 12, No 1 (2023) Neurobiological Effects of Chemical Compounds of Species of the Genus Astragalus L. and Prospects for Their Use in Medicine (Review) Abstract   PDF (Rus)
M. A. Berezutsky, N. A. Durnova, U. A. Matvienko
 
Vol 12, No 1 (2023) Evaluation of the Efficiency of a Soft Dosage Form for the Treatment of Osteoarthritis: Influence on the Level of Pro-inflammatory Cytokines Abstract   PDF (Rus)
U. V. Nogaeva, V. E. Kovanskov, D. Yu. Ivkin, E. V. Flisyuk, K. D. Yakimov, E. I. Yeletskaya, E. D. Semivelichenko, V. G. Antonov
 
Vol 12, No 1 (2023) Simultaneous Determination of Major Molnupiravir Metabolite (β-D-N4-hydroxycytidine) and Favipiravir in Human Plasma by HPLC-MS/MS Abstract   PDF (Rus)   PDF (Eng)
T. N. Komarov, P. K. Karnakova, O. A. Archakova, D. S. Shchelgacheva, N. S. Bagaeva, I. E. Shohin, K. Ya. Zaslavskaya, P. A. Bely
 
Vol 11, No 4 (2022): Supplement 1 Study of the Anti-inflammatory Activity of New Dosage Forms with Acyzol Abstract   PDF (Rus)
A. L. Golovanenko, I. P. Rudakova, E. S. Berezina, I. V. Alekseeva, E. I. Molokhova
 
Vol 11, No 4 (2022): Supplement 1 Study of Chronic Toxicity of Strawberry Garden (Fragaria ananassa) Leaves of Dry Extract Abstract   PDF (Rus)
O. V. Yaborоva, A. V. Kuritsyn, V. D. Belonogova, I. V. Alekseeva
 
Vol 11, No 4 (2022): Supplement 1 Development and Validation of the ELISA Method for Anti-trastuzumab Antibodies Determination in Human Serum Abstract   PDF (Rus)
O. A. Eliseeva, M. A. Kolganova, I. E. Shokhin, S. P. Dementyev, A. M. Vlasov, A. A. Zamyatnin, N. S. Dubovik, A. Yu. Savchenko, N. V. Dozmorova, V. G. Luzhanin
 
Vol 11, No 4 (2022) Clinical Testing of a New Radiopharmaceutical [99mТс]-Al2O3 for the Diagnosis of Sentinel Lymph Nodes Abstract   PDF (Rus)
А. A. Medvedeva, V. I. Chernov, R. V. Zelchan, O. D. Bragina, A. A. Rybina, V. S. Skuridin, E. S. Stasyuk, S. Yu. Chizhevskaya, A. V. Goldberg, E. Yu. Garbukov
 
Vol 11, No 4 (2022) Prognostic and Predictive Significance of mRNA Expression of ABC-transporter Genes in Patients with Non-small Cell Lung Cancer Abstract   PDF (Rus)
M. M. Tsyganov, M. K. Ibragimova, E. O. Rodionov, A. A. Frolova, S. V. Miller, O. V. Cheremisina, S. A. Tuzikov, N. V. Litvyakov
 
Vol 11, No 4 (2022) Development and Validation of Eltrombopag Determination in Human Plasma Blood by HPLC-MS Method Abstract   PDF (Rus)   PDF (Eng)
А. М. AL-Dhuraibi, A. L. Kulikov, M. V. Pokrovskiy
 
Vol 11, No 4 (2022) Approbation of a Model of Fat Liver Disease Induced by Orotic Acid Abstract   PDF (Rus)
V. V. Kovanskov, D. Yu. Ivkin, E. D. Semivelichenko, G. A. Plisko, E. A. Kopacheva, K. O. Sidorov
 
Vol 11, No 3 (2022) Development of a Method and a Scheme for the Use of a Live Recombinant Vaccine "GamLPV". Safety and Tolerability of Double Intranasal Vaccination of Healthy Adult Volunteers Abstract   PDF (Rus)
G. I. Karataev, A. Yu. Medkova, E. G. Semin, L. N. Sinyashina, R. A. Sioundioukova, S. V. Kulikov, N. A. Snegireva, I. N. Chernishova, M. V. Gavrilova, K. K. Bushkova, A. A. Lidzhieva, L. V. Kolobukhina, I. S. Kruzhkova, L. N. Merkulova, M. G. Rusanova, M. V. Bazarova, N. A. Antipyat, S. V. Smetanina, E. A. Smolyarchuk, I. N. Dyakov
 
Vol 11, No 3 (2022) Study of the Effectiveness of Drugs Based on Molecular Complexes of Adenosine-polymer on the Model of Thermal Burn Abstract   PDF (Rus)
E. D. Semivelichenko, A. A. Ermolaeva, V. V. Ponomarenko, A. V. Novoselov, G. A. Plisko, D. Yu. Ivkin, V. G. Antonov, V. E. Karev, I. A. Titovich, A. V. Eremin
 
Vol 11, No 3 (2022) Development and Validation of HPLC-UV Method for the Determination of Favipiravir in Human Plasma Abstract   PDF (Rus)   PDF (Eng)
T. N. Komarov, P. K. Karnakova, O. A. Archakova, D. S. Shchelgacheva, N. S. Bagaeva, I. E. Shohin, K. Ya. Zaslavskaya, P. A. Bely
 
Vol 11, No 3 (2022) Caco-2 Intestinal Permeability Study of Phenyltetrahydroquinolinedione Derivative – TRPA₁ Antagonist Abstract   PDF (Rus)
N. V. Pyatigorskaya, A. D. Kravchenko
 
Vol 11, No 2 (2022) Modulation of Rage and CD147 in Cerebral Amyloid Angiopathy in vitro Abstract   PDF (Rus)
A. I. Mosiagina, E. B. Boytsova, E. D. Khilazheva, E. A. Teplyashina, A. V. Morgun, A. B. Salmina
 
Vol 11, No 2 (2022) Study of the Role of Heparin in Regulation of the Morphofunctional Properties of MSC in Vitro Abstract   PDF (Eng)
I. K. Norkin, K. A. Yurova, O. G. Khaziakhmatova, E. S. Melashchenko, V. V. Malashchenko, E. O. Shunkin, A. N. Baikov, I. A. Khlusov, L. S. Litvinova
 
Vol 11, No 2 (2022) Phase I Pharmacokinetics Study of Drug «COVID-globulin» (Specific Human Immunoglobulin Against COVID-19) Abstract   PDF (Rus)   PDF (Eng)
T. I. Smolyanova, N. S. Bagaeva, M. A. Kolganova, I. E. Shohin, A. M. Nikolaeva, T. V. Vyaznikova, A. A. Pankratova, E. A. Bykova
 
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